Trichinosis is a parasitic disease caused by the nematode roundworms Trichinella spiralis. The disease is manifested by fever, the development of edema, muscle pain, and a high content of eosinophils is noted in the complete blood count during laboratory examination. In severe cases, damage to the myocardium of the heart and the central nervous system is possible.

The test IgG Determination For Trichinella Spiralis refers to the serological diagnosis of parasitic infections. The test material is blood, in which antibodies to the pathogen are detected. Antibodies are components of the body's immune system that are produced to destroy a particular foreign protein-antigen. In this case, the antigen is Trichinella.

There are several types of antibodies:

• IgA
• IgD
• IgE
• IgG
• IgM

However, the immune system cannot always cope with Trichinosis, even with very high concentrations of antibodies. Each of these antibodies has its own function and its own period of occurrence. Specific antibodies appear in the blood during the migration of trichinella larvae and their accumulation in the muscles.

Antibodies can be detected 15-20 days after infection when eating infected meat of domestic animals (pork) with high or medium contamination (50-100 larvae per 1g of meat). With a lower intensity of invasion, the timing of IgG detection can be significantly prolonged. When infected through the meat of wild animals (bear, wild boar, badger) antibodies are detected after 5 weeks.

Within 2-4 months, the concentration of antibodies increases, and then begins to decrease, but remains at the diagnostic level for at least one and a half years, with intensive invasion — for more than 2 years. The serological diagnosis of trichinosis can be made based on a 4-fold increase in the titer of specific IgG.