Complete Blood Count (CBC) is the most common laboratory test used for the quantitative and qualitative assessment of the main classes of the formed element of the blood. The examination includes the determination of hemoglobin level, haematocrit value, concentration of the formed element of the blood (erythrocytic indexwith the calculation of erythrocytic indexes - MCV, RDW, MCH, MCHC, leukocytes, platelets).
Traditionally, to assess the presence/absence of inflammatory processes in the body, the erythrocyte sedimentation rate (ESR) was previously determined together with the CBC. For more than a hundred years, this test has been used to determine the severity of inflammatory processes caused by infections, inflammation of various etiologies, and the development of neoplasms.
However, although inflammation is the most common cause of acceleration (increase) of erythrocyte sedimentation, an increase in sedimentation may also be caused by other, including not always pathological, conditions. As a consequence, the results of ESR determination can be considered reliable only when no other parameters, except for the presumed ones, affect the examined index.
C-reactive protein (CRP) is a protein that is one of the first to be produced in the body in response to inflammation or cell death. Unlike ESR, CRP is the most specific and most sensitive qualitative and quantitative laboratory indicator of inflammation and necrosis: CRP rises much earlier and decreases faster (CRP - 6-10 days; ESR- 2-4 weeks).
This explains the wide application of the analysis in monitoring and controlling the effectiveness of therapy of bacterial and viral infections, chronic inflammatory diseases, oncological diseases, complications in surgery and gynecology, etc. The analysis is widely used in monitoring and controlling the effectiveness of therapy of bacterial and viral infections, chronic inflammatory diseases, oncological diseases, complications in surgery and gynecology.